Osseointegration of zirconia implants: an SEM observation of the bone-implant interface
Identifieur interne : 005F32 ( Main/Exploration ); précédent : 005F31; suivant : 005F33Osseointegration of zirconia implants: an SEM observation of the bone-implant interface
Auteurs : Rita Depprich [Allemagne] ; Holger Zipprich [Allemagne] ; Michelle Ommerborn [Allemagne] ; Eduardo Mahn [Allemagne] ; Lydia Lammers [Allemagne] ; Jörg Handschel [Allemagne] ; Christian Naujoks [Allemagne] ; Hans-Peter Wiesmann [Allemagne] ; Norbert R. Kübler [Allemagne] ; Ulrich Meyer [Allemagne]Source :
- Head & Face Medicine [ 1746-160X ] ; 2008.
Abstract
The successful use of zirconia ceramics in orthopedic surgery led to a demand for dental zirconium-based implant systems. Because of its excellent biomechanical characteristics, biocompatibility, and bright tooth-like color, zirconia (zirconium dioxide, ZrO2) has the potential to become a substitute for titanium as dental implant material. The present study aimed at investigating the osseointegration of zirconia implants with modified ablative surface at an ultrastructural level.
A total of 24 zirconia implants with modified ablative surfaces and 24 titanium implants all of similar shape and surface structure were inserted into the tibia of 12 Göttinger minipigs. Block biopsies were harvested 1 week, 4 weeks or 12 weeks (four animals each) after surgery. Scanning electron microscopy (SEM) analysis was performed at the bone implant interface.
Remarkable bone attachment was already seen after 1 week which increased further to intimate bone contact after 4 weeks, observed on both zirconia and titanium implant surfaces. After 12 weeks, osseointegration without interposition of an interfacial layer was detected. At the ultrastructural level, there was no obvious difference between the osseointegration of zirconia implants with modified ablative surfaces and titanium implants with a similar surface topography.
The results of this study indicate similar osseointegration of zirconia and titanium implants at the ultrastructural level.
Url:
DOI: 10.1186/1746-160X-4-25
PubMed: 18990214
PubMed Central: 2583968
Affiliations:
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Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Zipprich, Holger" sort="Zipprich, Holger" uniqKey="Zipprich H" first="Holger" last="Zipprich">Holger Zipprich</name><affiliation wicri:level="1"><nlm:aff id="I2">Department for Prosthetic Dentistry, Section of Materials Sciences, Johann Wolfgang Goethe University Frankfurt, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Prosthetic Dentistry, Section of Materials Sciences, Johann Wolfgang Goethe University Frankfurt</wicri:regionArea><wicri:noRegion>Johann Wolfgang Goethe University Frankfurt</wicri:noRegion><wicri:noRegion>Johann Wolfgang Goethe University Frankfurt</wicri:noRegion><wicri:noRegion>Johann Wolfgang Goethe University Frankfurt</wicri:noRegion></affiliation></author><author><name sortKey="Ommerborn, Michelle" sort="Ommerborn, Michelle" uniqKey="Ommerborn M" first="Michelle" last="Ommerborn">Michelle Ommerborn</name><affiliation wicri:level="1"><nlm:aff id="I3">Department for Operative and Preventive Dentistry and Endodontics, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Operative and Preventive Dentistry and Endodontics, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Mahn, Eduardo" sort="Mahn, Eduardo" uniqKey="Mahn E" first="Eduardo" last="Mahn">Eduardo Mahn</name><affiliation wicri:level="1"><nlm:aff id="I1">Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Lammers, Lydia" sort="Lammers, Lydia" uniqKey="Lammers L" first="Lydia" last="Lammers">Lydia Lammers</name><affiliation wicri:level="1"><nlm:aff id="I4">Department for Cranio- and Maxillofacial Surgery, Westfalian Wilhelms-University Muenster, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Westfalian Wilhelms-University Muenster</wicri:regionArea><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion></affiliation></author><author><name sortKey="Handschel, Jorg" sort="Handschel, Jorg" uniqKey="Handschel J" first="Jörg" last="Handschel">Jörg Handschel</name><affiliation wicri:level="1"><nlm:aff id="I1">Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Naujoks, Christian" sort="Naujoks, Christian" uniqKey="Naujoks C" first="Christian" last="Naujoks">Christian Naujoks</name><affiliation wicri:level="1"><nlm:aff id="I1">Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Wiesmann, Hans Peter" sort="Wiesmann, Hans Peter" uniqKey="Wiesmann H" first="Hans-Peter" last="Wiesmann">Hans-Peter Wiesmann</name><affiliation wicri:level="1"><nlm:aff id="I4">Department for Cranio- and Maxillofacial Surgery, Westfalian Wilhelms-University Muenster, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Westfalian Wilhelms-University Muenster</wicri:regionArea><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion><wicri:noRegion>Westfalian Wilhelms-University Muenster</wicri:noRegion></affiliation></author><author><name sortKey="Kubler, Norbert R" sort="Kubler, Norbert R" uniqKey="Kubler N" first="Norbert R" last="Kübler">Norbert R. Kübler</name><affiliation wicri:level="1"><nlm:aff id="I1">Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Meyer, Ulrich" sort="Meyer, Ulrich" uniqKey="Meyer U" first="Ulrich" last="Meyer">Ulrich Meyer</name><affiliation wicri:level="1"><nlm:aff id="I1">Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Duesseldorf</wicri:regionArea><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion><wicri:noRegion>Heinrich-Heine-University Duesseldorf</wicri:noRegion></affiliation></author></analytic><series><title level="j">Head & Face Medicine</title><idno type="eISSN">1746-160X</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The successful use of zirconia ceramics in orthopedic surgery led to a demand for dental zirconium-based implant systems. Because of its excellent biomechanical characteristics, biocompatibility, and bright tooth-like color, zirconia (zirconium dioxide, ZrO<sub>2</sub>) has the potential to become a substitute for titanium as dental implant material. The present study aimed at investigating the osseointegration of zirconia implants with modified ablative surface at an ultrastructural level.</p></sec><sec sec-type="methods"><title>Methods</title><p>A total of 24 zirconia implants with modified ablative surfaces and 24 titanium implants all of similar shape and surface structure were inserted into the tibia of 12 Göttinger minipigs. Block biopsies were harvested 1 week, 4 weeks or 12 weeks (four animals each) after surgery. Scanning electron microscopy (SEM) analysis was performed at the bone implant interface.</p></sec><sec><title>Results</title><p>Remarkable bone attachment was already seen after 1 week which increased further to intimate bone contact after 4 weeks, observed on both zirconia and titanium implant surfaces. After 12 weeks, osseointegration without interposition of an interfacial layer was detected. At the ultrastructural level, there was no obvious difference between the osseointegration of zirconia implants with modified ablative surfaces and titanium implants with a similar surface topography.</p></sec><sec><title>Conclusion</title><p>The results of this study indicate similar osseointegration of zirconia and titanium implants at the ultrastructural level.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Depprich, Rita" sort="Depprich, Rita" uniqKey="Depprich R" first="Rita" last="Depprich">Rita Depprich</name></noRegion><name sortKey="Handschel, Jorg" sort="Handschel, Jorg" uniqKey="Handschel J" first="Jörg" last="Handschel">Jörg Handschel</name><name sortKey="Kubler, Norbert R" sort="Kubler, Norbert R" uniqKey="Kubler N" first="Norbert R" last="Kübler">Norbert R. Kübler</name><name sortKey="Lammers, Lydia" sort="Lammers, Lydia" uniqKey="Lammers L" first="Lydia" last="Lammers">Lydia Lammers</name><name sortKey="Mahn, Eduardo" sort="Mahn, Eduardo" uniqKey="Mahn E" first="Eduardo" last="Mahn">Eduardo Mahn</name><name sortKey="Meyer, Ulrich" sort="Meyer, Ulrich" uniqKey="Meyer U" first="Ulrich" last="Meyer">Ulrich Meyer</name><name sortKey="Naujoks, Christian" sort="Naujoks, Christian" uniqKey="Naujoks C" first="Christian" last="Naujoks">Christian Naujoks</name><name sortKey="Ommerborn, Michelle" sort="Ommerborn, Michelle" uniqKey="Ommerborn M" first="Michelle" last="Ommerborn">Michelle Ommerborn</name><name sortKey="Wiesmann, Hans Peter" sort="Wiesmann, Hans Peter" uniqKey="Wiesmann H" first="Hans-Peter" last="Wiesmann">Hans-Peter Wiesmann</name><name sortKey="Zipprich, Holger" sort="Zipprich, Holger" uniqKey="Zipprich H" first="Holger" last="Zipprich">Holger Zipprich</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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